A Continuous Time GARCH Process of Higher Order

A continuous time GARCH model of order (p,q) is introduced, which is driven by a single Lévy process. It extends many of the features of discrete time GARCH(p,q) processes to a continuous time setting. When p=q=1, the process thus defined reduces to the COGARCH(1,1) process of Klüppelberg, Lindner and Maller (2004). We give sufficient conditions for the existence of stationary solutions and show that the volatility process has the same autocorrelation structure as a continuous time ARMA process. The autocorrelation of the squared increments of the process is also investigated, and conditions ensuring a positive volatility are discussed

Linear prediction of ARMA processes with infinite variance

AbstractIn order to predict unobserved values of a linear process with infinite variance, we introduce a linear predictor which minimizes the dispersion (suitably defined) of the error distribution. When the linear process is driven by symmetric stable white noise this predictor minimizes the scale parameter of the error distribution. In the more general case when the driving white noise process has regularly varying tails with index α, the predictor minimizes the size of the error tail probabilities. The procedure can be interpreted also as minimizing an appropriately defined lα-distance between the predictor and the random variable to be predicted. We derive explicitly the best linear predictor of Xn+1 in terms of X1,..., Xn for the process ARMA(1, 1) and for the process AR(p). For higher order processes general analytic expressions are cumbersome, but we indicate how predictors can be determined numerically

Parametric estimation of the driving L\'evy process of multivariate CARMA processes from discrete observations

We consider the parametric estimation of the driving L\'evy process of a multivariate continuous-time autoregressive moving average (MCARMA) process, which is observed on the discrete time grid $(0,h,2h,...)$. Beginning with a new state space representation, we develop a method to recover the driving L\'evy process exactly from a continuous record of the observed MCARMA process. We use tools from numerical analysis and the theory of infinitely divisible distributions to extend this result to allow for the approximate recovery of unit increments of the driving L\'evy process from discrete-time observations of the MCARMA process. We show that, if the sampling interval $h=h_N$ is chosen dependent on $N$, the length of the observation horizon, such that $N h_N$ converges to zero as $N$ tends to infinity, then any suitable generalized method of moments estimator based on this reconstructed sample of unit increments has the same asymptotic distribution as the one based on the true increments, and is, in particular, asymptotically normally distributed.Comment: 38 pages, four figures; to appear in Journal of Multivariate Analysi

Unfolding dynamics of proteins under applied force

Understanding the mechanisms of protein folding is a major challenge that is being addressed effectively by collaboration between researchers in the physical and life sciences. Recently, it has become possible to mechanically unfold proteins by pulling on their two termini using local force probes such as the atomic force microscope. Here, we present data from experiments in which synthetic protein polymers designed to mimic naturally occurring polyproteins have been mechanically unfolded. For many years protein folding dynamics have been studied using chemical denaturation, and we therefore firstly discuss our mechanical unfolding data in the context of such experiments and show that the two unfolding mechanisms are not the same, at least for the proteins studied here. We also report unexpected observations that indicate a history effect in the observed unfolding forces of polymeric proteins and explain this in terms of the changing number of domains remaining to unfold and the increasing compliance of the lengthening unstructured polypeptide chain produced each time a domain unfolds

Symbiotic Effectiveness of Rhizobial Mutualists Varies in Interactions with Native Australian Legume Genera

Peer reviewe

DFSeer: A visual analytics approach to facilitate model selection for demand forecasting

Selecting an appropriate model to forecast product demand is critical to the manufacturing industry. However, due to the data complexity, market uncertainty and users' demanding requirements for the model, it is challenging for demand analysts to select a proper model. Although existing model selection methods can reduce the manual burden to some extent, they often fail to present model performance details on individual products and reveal the potential risk of the selected model. This paper presents DFSeer, an interactive visualization system to conduct reliable model selection for demand forecasting based on the products with similar historical demand. It supports model comparison and selection with different levels of details. Besides, it shows the difference in model performance on similar products to reveal the risk of model selection and increase users' confidence in choosing a forecasting model. Two case studies and interviews with domain experts demonstrate the effectiveness and usability of DFSeer.Comment: 10 pages, 5 figures, ACM CHI 202

The disruption of proteostasis in neurodegenerative diseases

Cells count on surveillance systems to monitor and protect the cellular proteome which, besides being highly heterogeneous, is constantly being challenged by intrinsic and environmental factors. In this context, the proteostasis network (PN) is essential to achieve a stable and functional proteome. Disruption of the PN is associated with aging and can lead to and/or potentiate the occurrence of many neurodegenerative diseases (ND). This not only emphasizes the importance of the PN in health span and aging but also how its modulation can be a potential target for intervention and treatment of human diseases.info:eu-repo/semantics/publishedVersio

Gaussian maximum likelihood estimation for ARMA models II: spatial processes

This paper examines the Gaussian maximum likelihood estimator (GMLE) in the context of a general form of spatial autoregressive and moving average (ARMA) processes with finite second moment. The ARMA processes are supposed to be causal and invertible under the half-plane unilateral order, but not necessarily Gaussian. We show that the GMLE is consistent. Subject to a modification to confine the edge effect, it is also asymptotically distribution-free in the sense that the limit distribution is normal, unbiased and has variance depending only on the autocorrelation function. This is an analogue of Hannan's classic result for time series in the context of spatial processes